Think daytime fatigue is due to sleep loss? Think again.
Posted on 31. Aug, 2010 by Guy in Nutrition & Lifestyle
by Benjamin Brown N.D
Excessive daytime sleepiness and fatigue is one of the most common sleep disorders and although classically thought to be due to sleep loss new research suggests otherwise.
A large scale study has found that excessive daytime sleepiness (EDS) is strongly related to disrupted metabolism and not sleep loss at all.
If not sleep loss, what is it?
In a study of over 15,000 people a group of investigators set out to find associations between risk factors for EDS and its severity in a hope to help identify the underlying mechanisms. Remarkably it was found that contrary to popular thought sleep disorder breathing and sleep disruption did not carry nearly as much risk for EDS as diabetes, obesity and depression. 
In a study of over 15,000 people a group of investigators set out to find associations between risk factors for EDS and its severity in a hope to help identify the underlying mechanisms. Remarkably it was found th
at contrary to popular thought sleep disorder breathing and sleep disruption did not carry nearly as much risk for EDS as diabetes, obesity and depression.
Metabolic disruption causes fatigue
Something that depression, diabetes and obesity have in common is shared features of disrupted metabolism including disturbance of circadian rhythms of hormones and cytokines. This understanding creates a new view of the mechanisms underlying fatigue and opens an avenue for the successful management of EDS.
Something that depression, diabetes and obesity have in common is shared features of disrupted metabolism including disturbance of circadian rhythms of hormones and cytokines. This understanding creates a new view of the mechanisms underlying fatigue and opens an avenue for the successful management of EDS.
McEwen BS. Sleep deprivation as a neurobiologic and physiologic stressor: Allostasis and allostatic load. Metabolism. 2006 Oct;55(10 Suppl 2):S20-3.
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